Red Sox third baseman Alex Bregman was removed in the fifth inning of Friday's opening game of a doubleheader against the Baltimore Orioles after what appeared to be a lower-body injury.

There are a handful of players the Red Sox cannot afford to be without, and Friday afternoon the club may have lost the most indispensable of all. Red Sox third baseman Alex Bregman left Friday’s game with an apparent injury during the bottom of the fifth inning.

Bregman roped a single to left field in the fifth inning, rounded first base, then immediately called for the trainer and exited the game with a slight limp. Bregman told reporters on Saturday that he felt worse than expected. He subsequently underwent an MRI before being placed on the shelf.