Journal of Neurology, Neurosurgery and Psychiatry (JNNP)'s ambition is to publish the most ground-breaking and cutting-edge research from around the world. Encompassing the entire genre of ...

Objectives This longitudinal study compared emerging plasma biomarkers for neurodegenerative disease between controls, patients with Alzheimer’s disease (AD), Lewy body dementia (LBD), frontotemporal ...

A 44-year-old, post-transplant female, presented with urosepsis and raised tacrolimus level. She developed focal motor seizures. She suffered long-standing type-1 diabetes, developing end-stage renal ...

The Grey Walter Department of Clinical Neurophysiology, Frenchay Hospital, Bristol, UK Correspondence to: Dr Nick Kane The Grey Walter Department of Clinical Neurophysiology, Frenchay Hospital, ...

Introduction The cerebellum has strong cortical and subcortical connectivity, but is rarely taken into account for clinical diagnosis in many neurodegenerative conditions, particularly in the absence ...

Parkinson’s disease (PD) is an incurable and progressive neurological disorder leading to deleterious motor and non-motor consequences. Presently, no pharmacological agents can prevent PD evolution or ...

Background Cognitive and behavioural dysfunction may occur in people with motor neuron disease (MND), with some studies suggesting an association with the C9ORF72 repeat expansion. Their onset and ...

Parkinson’s disease and related disorders (PDRD) are the second most common neurodegenerative disease and a leading cause of death. However, patients with PDRD receive less end-of-life palliative care ...

Correspondence to Dr Sameer A Sheth, Department of Neurosurgery, Baylor College of Medicine, Houston, TX 77030, USA; Sameer.Sheth{at}bcm.edu Deep brain stimulation (DBS) is an established and growing ...

The objective of this paper is to evaluate available evidence for each step in autoimmune encephalitis management and provide expert opinion when evidence is lacking. The paper approaches autoimmune ...

Objective Gait disturbance lowers activities of daily living in patients with Parkinson’s disease (PD) and related disorders. However, the effectiveness of pharmacological, surgical and rehabilitative ...

Objective Imaging is recommended to support the clinical diagnoses of dementias, yet imaging research studies rarely have pathological confirmation of disease. This study aims to characterise patterns ...