Nevertheless, Dane remains hopeful. “I’m fighting as much as I can,” Dane said. “There’s so much about it that’s out of my control.” Later, he added, “In my heart I don’t feel like this is the end of me.”

Dane -- who shot to fame amid six seasons on the hit ABC drama "Grey's Anatomy," where he played Dr. Mark Sloan, affectionately known as "McSteamy" -- said his symptoms began over one year ago, when he began to experience weakness in his right hand.

In an emotional interview with Diane Sawyer, Eric Dane revealed he has "one functioning arm" amid his battle with ALS.